IL4R monoclonal antibody (M01), clone 1D3-抗体-抗体-生物在线

产品名称： IL4R monoclonal antibody (M01), clone 1D3

英文名称： IL4R monoclonal antibody (M01), clone 1D3

产品编号： H00003566-M01

产品价格： null

产品产地：台湾

品牌商标： Abnova

更新时间： null

使用范围：

亚诺法生技股份有限公司（Abnova)

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Immunogen:
IL4R (NP_000409, 26 a.a. ~ 135 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence:
MKVLQEPTCVSDYMSISTCEWKMNGPTNCSTELRLLYQLVFLLSEAHTCIPENNGGAGCVCHLLMDDVVSADNYTLDLWAGQQLLWKGSFKPSEHVKPRAPGNLTVHTNV

Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged IL4R is 0.1 ng/ml as a capture antibody.
Protocol Download

Gene Summary:
This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by an alternate splice variant or by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Two transcript variants encoding different isoforms, a membrane-bound and a soluble form, have been found for this gene. [provided by RefSeq

Other Designations:
OTTHUMP00000122506,interleukin 4 receptor alpha chain,interleukin-4 receptor alpha chain