BAK1 polyclonal antibody
产品名称: BAK1 polyclonal antibody
英文名称: BAK1 polyclonal antibody
产品编号: PAB19525
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of BAK1.
- Immunogen:
- A synthetic peptide corresponding to amino acids 74-95 at middle region of human BAK1.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Specificity:
- It different from the related mouse and rat sequence by one amino acid.
- Form:
- Lyophilized
- Purification:
- Immunoaffinity purification
- Storage Buffer:
- Lyophilized from 0.9 mg NaCl, 0.2 mg Na2HPO4 (5 mg BSA, 0.05 mg sodium azide, 0.05 mg Thimerosal)
- Storage Instruction:
- Store at -20°C on dry atmosphere.
After reconstitution with 200 uL of deionized water and concentration will be 500 ug/mL, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1 ug/mL)
Immunocytochemistry (1 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide and thimerosal: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Application Image
- Western Blot (Cell lysate)
- enlarge
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Immunocytochemistry
- Entrez GeneID:
- 578
- Gene Name:
- BAK1
- Gene Alias:
- BAK,BAK-LIKE,BCL2L7,CDN1,MGC117255,MGC3887
- Gene Description:
- BCL2-antagonist/killer 1
- Omim ID:
- 600516
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq
- Other Designations:
- BCL2-like 7 protein,Bcl-2 homologous antagonist/killer,OTTHUMP00000016211,OTTHUMP00000039620,apoptosis regulator BAK,pro-apoptotic protein BAK
- Related Disease
- Adenocarcinoma
- Arthritis, Rheumatoid
- Ataxia Telangiectasia
- Autoimmune Diseases
- Cardiovascular Diseases
- Diabetes Mellitus, Type 2
- Disease Progression
- Edema
- Esophageal Neoplasms
- Genetic Predisposition to Disease
- Kidney Failure, Chronic
- Lung Neoplasms
- Lupus Erythematosus, Systemic
- Lymphoma, Non-Hodgkin
- Lymphoproliferative Disorders
- Pulmonary Disease, Chronic Obstructive
- Rheumatic Diseases
- Sjogren's Syndrome
- Urinary Bladder Neoplasms