BMF polyclonal antibody
产品名称： BMF polyclonal antibody
英文名称： BMF polyclonal antibody
产品编号： PAB14573
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of BMF.
- Immunogen:
- A synthetic peptide corresponding to amino acids 2-14 of human BMF.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Specificity:
- Bmf antibody will cross-react with mouse and rat, based on NCBI BLAST.
- Form:
- Liquid
- Storage Buffer:
- In serum (50% glycerol, 0.05% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:100-1:1000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins.
Puthalakath H, Strasser A.Cell Death Differ. 2002 May;9(5):505-12.
- 2.
- Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis.
Puthalakath H, Villunger A, O'Reilly LA, Beaumont JG, Coultas L, Cheney RE, Huang DC, Strasser A.Science. 2001 Sep 7;293(5536):1829-32.
- Application Image
- ELISA
- Entrez GeneID:
- 90427
- Protein Accession#:
- NP_001003943
- Gene Name:
- BMF
- Gene Alias:
- FLJ00065
- Gene Description:
- Bcl2 modifying factor
- Omim ID:
- 606266
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a single BCL2 homology domain 3 (BH3), and has been shown to bind BCL2 proteins and function as an apoptotic activator. This protein is found to be sequestered to myosin V motors by its association with dynein light chain 2, which may be important for sensing intracellular damage and triggering apoptosis. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
- Other Designations:
- -