SIRT7 (C-term) Peptide
产品名称： SIRT7 (C-term) Peptide
英文名称： SIRT7 (C-term) Peptide
产品编号： P1851
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of SIRT7.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human SIRT7.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins.
Frye RA.Biochem Biophys Res Commun. 2000 Jul 5;273(2):793-8.
- Applications
- Western Blot (Tissue lysate)
- Western blot analysis of SIRT7 polyclonal antibody (Cat # PAB4826) in placenta tissue lysate (35 ug/lane). SIRT7 (arrow) was detected using the purified polyclonal antibody.
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with SIRT7 polyclonal antibody (Cat # PAB4826) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. HC = hepatocarcinoma.
- Entrez GeneID:
- 51547
- Protein Accession#:
- NP_057622;Q9NRC8
- Gene Name:
- SIRT7
- Gene Alias:
- MGC126840,MGC126842,SIR2L7
- Gene Description:
- sirtuin (silent mating type information regulation 2 homolog) 7 (S. cerevisiae)
- Omim ID:
- 606212
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. [provided by RefSeq
- Other Designations:
- silent mating type information regulation 2, S.cerevisiae, homolog 7,sir2-related protein type 7,sirtuin 7,sirtuin type 7