IL15 purified MaxPab rabbit polyclonal antibody (D01P)
产品名称: IL15 purified MaxPab rabbit polyclonal antibody (D01P)
英文名称: IL15 purified MaxPab rabbit polyclonal antibody (D01P)
产品编号: H00003600-D01P
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against a full-length human IL15 protein.
- Immunogen:
- IL15 (NP_000576.1, 1 a.a. ~ 162 a.a) full-length human protein.
- Sequence:
- MRISKPHLRSISIQCYLCLLLNSHFLTEAGIHVFILGCFSAGLPKTEANWVNVISDLKKIEDLIQSMHIDATLYTESDVHPSCKVTAMKCFLLELQVISLESGDASIHDTVENLIILANNSLSSNGNVTESGCKECEELEEKNIKEFLQSFVHIVQMFINTS
- Host:
- Rabbit
- Reactivity:
- Human
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- MSDS:
- Download
- Applications
- Western Blot (Transfected lysate)
- Western Blot analysis of IL15 expression in transfected 293T cell line (H00003600-T01) by IL15 MaxPab polyclonal antibody.
Lane 1: IL15 transfected lysate(18.10 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Entrez GeneID:
- 3600
- GeneBank Accession#:
- NM_000585
- Protein Accession#:
- NP_000576.1
- Gene Name:
- IL15
- Gene Alias:
- IL-15,MGC9721
- Gene Description:
- interleukin 15
- Omim ID:
- 600554
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported. [provided by RefSeq
- Other Designations:
- OTTHUMP00000164617
- Related Disease
- Adenocarcinoma
- Arthritis, Rheumatoid
- Asthma
- Asthma
- Bronchial Hyperreactivity
- Bronchiolitis, Viral
- Carcinoma, Non-Small-Cell Lung
- Cardiovascular Diseases
- Celiac Disease
- Connective Tissue Diseases
- Coronary Disease
- Diabetes Mellitus
- Diabetes Mellitus, Type 2
- Edema
- Esophageal Neoplasms
- Fetal Diseases
- Fractures, Bone
- Genetic Predisposition to Disease
- Hematologic Diseases