IL5 (Human) Recombinant Protein (Q01)
产品名称: IL5 (Human) Recombinant Protein (Q01)
英文名称: IL5 (Human) Recombinant Protein (Q01)
产品编号: H00003567-Q01
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
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- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human IL5 partial ORF ( NP_000870, 20 a.a. - 134 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- IPTEIPTSALVKETLALLSTHRTLLIANETLRIPVPVHKNHQLCTEEIFQGIGTLESQTVQGGTVERLFKNLSLIKKYIDGQKKKCGEERRRVNQFLDYLQEFLGVMNTEWIIES
- Theoretical MW (kDa):
- 38.39
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
- Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 3567
- GeneBank Accession#:
- NM_000879
- Protein Accession#:
- NP_000870
- Gene Name:
- IL5
- Gene Alias:
- EDF,IL-5,TRF
- Gene Description:
- interleukin 5 (colony-stimulating factor, eosinophil)
- Omim ID:
- 147850
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. This cytokine is a main regulator of eosinopoiesis, eosinophil maturation and activation. The elevated production of this cytokine is reported to be related to asthma or hypereosinophilic syndromes. The receptor of this cytokine is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene, together with those for interleukin 4 (IL4), interleukin 13 (IL13), and CSF2, form a cytokine gene cluster on chromosome 5. This cytokine, IL4, and IL13 are found to be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31. [provided by RefSeq
- Other Designations:
- B cell differentiation factor I,OTTHUMP00000065830,T-cell replacing factor,eosinophil differentiation factor,interleukin 5,interleukin-5
- Related Disease
- Adenocarcinoma
- Asthma
- Asthma
- Bacteremia
- Biliary Tract Neoplasms
- Breast Neoplasms
- Bronchial Hyperreactivity
- Bronchiolitis, Viral
- Carcinoma, Non-Small-Cell Lung
- Cardiovascular Diseases
- Celiac Disease
- Chorioamnionitis
- Colitis, Ulcerative
- Connective Tissue Diseases
- Crohn Disease
- Crohn's disease
- Dermatitis, Atopic
- Diabetes Mellitus, Type 2
- Ductus Arteriosus, Patent