PCSK1 monoclonal antibody (M02), clone 3D2
产品名称: PCSK1 monoclonal antibody (M02), clone 3D2
英文名称: PCSK1 monoclonal antibody (M02), clone 3D2
产品编号: H00005122-M02
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant PCSK1.
- Immunogen:
- PCSK1 (NP_000430, 652 a.a. ~ 753 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- GGRRDELEEGAPSEAMLRLLQSAFSKNSPPKQSPKKSPTAKLNIPYENFYEALEKLNKPSQLKDSEDSLYNDYVDVFYNTKPYKHRDDRLLQALVDILNEEN
- Host:
- Mouse
- Reactivity:
- Human, Mouse, Rat
- Isotype:
- IgG3 Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.96 KDa) .
- MSDS:
- Download
- Applications
- Western Blot (Cell lysate)
- PCSK1 monoclonal antibody (M02), clone 3D2 Western Blot analysis of PCSK1 expression in HeLa ( Cat # L013V1 ).
- Protocol Download
- Western Blot (Cell lysate)
- PCSK1 monoclonal antibody (M02), clone 3D2. Western Blot analysis of PCSK1 expression in PC-12(Cat # L012V1 ).
- Protocol Download
- Western Blot (Cell lysate)
- PCSK1 monoclonal antibody (M02), clone 3D2. Western Blot analysis of PCSK1 expression in Raw 264.7(Cat # L024V1 ).
- Protocol Download
- Western Blot (Cell lysate)
- PCSK1 monoclonal antibody (M02), clone 3D2. Western Blot analysis of PCSK1 expression in NIH/3T3(Cat # L018V1 ).
- Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge this image
- Immunoperoxidase of monoclonal antibody to PCSK1 on formalin-fixed paraffin-embedded human small Intestine. [antibody concentration 3 ug/ml]
- Protocol Download
- Immunofluorescence
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- Immunofluorescence of monoclonal antibody to PCSK1 on HeLa cell. [antibody concentration 30 ug/ml]
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged PCSK1 is approximately 0.03ng/ml as a capture antibody.
- Protocol Download
- Application Image
- Western Blot (Cell lysate)
- enlarge
- Western Blot (Cell lysate)
- enlarge
- Western Blot (Cell lysate)
- enlarge
- Western Blot (Cell lysate)
- enlarge
- Western Blot (Recombinant protein)
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge
- Immunofluorescence
- enlarge
- Sandwich ELISA (Recombinant protein)
- enlarge
- ELISA
- Entrez GeneID:
- 5122
- GeneBank Accession#:
- NM_000439
- Protein Accession#:
- NP_000430
- Gene Name:
- PCSK1
- Gene Alias:
- BMIQ12,NEC1,PC1,PC3,SPC3
- Gene Description:
- proprotein convertase subtilisin/kexin type 1
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a type I proinsulin-processing enzyme that plays a key role in regulating insulin biosynthesis. It is also known to cleave proopiomelanocortin, prorenin, proenkephalin, prodynorphin, prosomatostatin and progastrin. Mutations in this gene are thought to cause obesity. This encoded protein is associated with carcinoid tumors. The use of alternate polyadenylation sites has been found for this gene. Multiple alternatively spliced transcript variants have been described for this gene but their full length nature is not known. [provided by RefSeq
- Other Designations:
- neuroendocrine convertase 1,prohormone convertase 1,prohormone convertase 3,proprotein convertase 1
- Related Disease
- Albuminuria
- Alzheimer Disease
- Alzheimer disease
- Birth Weight
- Body Weight
- Cardiovascular Diseases
- Diabetes Complications
- Diabetes Mellitus, Type 1
- Diabetes Mellitus, Type 2
- Diabetic Nephropathies
- Disease Progression
- Edema
- Genetic Predisposition to Disease
- Glucose Intolerance
- Hyperinsulinism
- Hypertension
- Insulin Resistance
- Metabolic Syndrome X
- Neoplasms