FITC标记的磷酸化驱动蛋白家族成员22抗体
产品名称: FITC标记的磷酸化驱动蛋白家族成员22抗体
英文名称: Anti-phospho-KIF22 (Ser427)/FITC
产品编号: HZ-17050R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: ICC=1:50-200 IF=1:50-200
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Rabbit Anti-phospho-KIF22 (Ser427)/FITC Conjugated antibody
FITC标记的磷酸化驱动蛋白家族成员22抗体
英文名称 | Anti-phospho-KIF22 (Ser427)/FITC |
中文名称 | FITC标记的磷酸化驱动蛋白家族成员22抗体 |
别 名 | KIF22 (phospho S427); p-KIF22 (phospho S427); p-KID (Ser 427); A 328A3.2; KID; KIF 22; kif22; KIF22_HUMAN; Kinesin family member 22; Kinesin like 4; Kinesin like DNA binding protein; Kinesin like DNA binding protein pseudogene; Kinesin like protein 4; Kinesin like protein KIF22; Kinesin-like DNA-binding protein; Kinesin-like protein 4; Kinesin-like protein KIF22; KNSL 4; KNSL4; OBP 1; OBP 2; OBP; OBP1; OBP2; Origin of plasmid DNA replication binding protein; OriP binding protein; OTTHUMP00000123406. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
产品类型 | 磷酸化抗体 |
研究领域 | 细胞生物 免疫学 信号转导 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Dog, Cow, Horse, Sheep, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 73kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated Synthesised phosphopeptide derived from human KIF22 around the phosphorylation site of Ser427 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: The protein encoded by this gene is a member of the kinesin-like protein family. The family members are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. The C-terminal half of this protein has been shown to bind DNA. Studies with the Xenopus homolog suggests its essential role in metaphase chromosome alignment and maintenance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] Function: Kinesin family that is involved in spindle formation and the movements of chromosomes during mitosis and meiosis. Binds to microtubules and to DNA. Subcellular Location: Nucleus. Cytoplasm > cytoskeleton. Post-translational modifications: Ubiquitinated; mediated by SIAH1 and leading to its subsequent proteasomal degradation. Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: Belongs to the kinesin-like protein family. Contains 1 kinesin-motor domain. Database links: Entrez Gene: 3835 Human Omim: 603213 Human SwissProt: Q14807 Human Unigene: 612151 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
由该基因编码的蛋白是驱动蛋白样蛋白家族的成员。家族成员是微管依赖的分子马达,在细胞内运输细胞器,并在细胞分裂过程中移动染色体。该蛋白的C-末端一半已显示结合DNA。爪蟾同源物的研究表明其在中期染色体排列和维持中的重要作用。另一种编码不同的异构体的剪接转录变体已被发现用于该基因。[ RefSeq,2012月1日]