Product Information
    
 
    

    

        

            

                

                
Product Name
                
                

                
Cat#
                
                

                
Size
                
                

                
Price（¥）
                
            
            

                

                
Recombinant Mouse Platelet-derived Growth Factor-BB (Mouse PDGF-BB)
                
                

                
91602ES10
                
                

                
10 μg
                
                

                
1855.00
                
            
            

                

                
91602ES60
                
                

                
100 μg
                
                

                
10215.00
                
            
            

                

                
91602ES76
                
                

                
500 μg
                
                

                
26545.00
                
            
        
    
    
    
 
    
Product Description
    
 
    
Platelet-derived growth factor (PDGF) was discovered as a major mitogenic factor present in serum but absent from plasma. In vitro, PDGF-BB stimulated MAP kinase activity and cell motility of isolated lymphatic endothelial cells. In vivo, PDGF-BB potently induced growth of lymphatic vessels. Expression of PDGF-BB in murine fibrosarcoma cells induced tumor lymphangiogenesis, leading to enhanced metastasis in lymph nodes. The PDGF signaling system contributes to and vascular remodeling. Growth factors such as PDGF exert potent effects on wound healing including the regeneration of tooth-supporting structures. Some research reports findings in this chronic myocardial infarction model were that bFGF, PDGF-BB and their combination all had a more pronounced angiogenic effect on the arteriolar than the capillary level. bFGF stimulated both capillary and arteriolar growth while PDGF-BB preferentially stimulated arterioles.
    
 
    
Product Properties
    
 
    

    

            

                

                    

                        

                            
                        
                    
                
            
        





























        

            

                

                
Synonyms
                
                

                
Becaplermin, ODGF, PDGF-2, PDGFBB, PDGF-BB
                
            
            

                

                
Accession
                
                

                
P31240
                
            
            

                

                
GeneID
                
                

                
18591
                
            
            

                

                
Source
                
                

                
E.coli-derived mouse PDGF-BB protein, Ser82-Thr190.
                
            
            

                

                
Molecular Weight
                
                

                
Approximately 24.4 kDa
                
            
            

                

                
AA Sequence
                
                

                
SLGSLAAAEP AVIAECKTRT EVFQISRNLI DRTNANFLVW PPCVEVQRCS GCCNNRNVQC RASQVQMRPV QVRKIEIVRK KPIFKKATVT LEDHLACKCE TIVTPRPVT
                
            
            

                

                
Tag
                
                

                
None
                
            
            

                

                
Physical Appearance
                
                

                
Sterile Filtered White lyophilized (freeze-dried) powder.