FGR (Human) Recombinant Protein (P01)
产品名称： FGR (Human) Recombinant Protein (P01)
英文名称： FGR (Human) Recombinant Protein (P01)
产品编号： H00002268-P01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human FGR full-length ORF ( NP_005239.1, 1 a.a. - 529 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- MGCVFCKKLEPVATAKEDAGLEGDFRSYGAADHYGPDPTKARPASSFAHIPNYSNFSSQAINPGFLDSGTIRGVSGIGVTLFIALYDYEARTEDDLTFTKGEKFHILNNTEGDWWEARSLSSGKTGCIPSNYVAPVDSIQAEEWYFGKIGRKDAERQLLSPGNPQGAFLIRESETTKGAYSLSIRDWDQTRGDHVKHYKIRKLDMGGYYITTRVQFNSVQELVQHYMEVNDGLCNLLIAPCTIMKPQTLGLAKDAWEISRSSITLERRLGTGCFGDVWLGTWNGSTKVAVKTLKPGTMSPKAFLEEAQVMKLLRHDKLVQLYAVVSEEPIYIVTEFMCHGSLLDFLKNPEGQDLRLPQLVDMAAQVAEGMAYMERMNYIHRDLRAANILVGERLACKIADFGLARLIKDDEYNPCQGSKFPIKWTAPEAALFGRFTIKSDVWSFGILLTELITKGRIPYPGMNKREVLEQVEQGYHMPCPPGCPASLYEAMEQTWRLDPEERPTFEYLQSFLEDYFTSAEPQYQPGDQT
- Theoretical MW (kDa):
- 85.9
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 2268
- GeneBank Accession#:
- NM_005248.2
- Protein Accession#:
- NP_005239.1
- Gene Name:
- FGR
- Gene Alias:
- FLJ43153,MGC75096,SRC2,c-fgr,c-src2,p55c-fgr,p58c-fgr
- Gene Description:
- Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
- Omim ID:
- 164940
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq
- Other Designations:
- OTTHUMP00000003601,OTTHUMP00000003602,OTTHUMP00000003603,c-fgr protooncogene,c-src-2 proto-oncogene,p55-c-fgr protein,proto-oncogene tyrosine-protein kinase FGR
- Gene Pathway
- Related Disease