Mapk14 (phospho T180/Y182) monoclonal antibody, clone M139
产品名称: Mapk14 (phospho T180/Y182) monoclonal antibody, clone M139
英文名称: Mapk14 (phospho T180/Y182) monoclonal antibody, clone M139
产品编号: MAB1385
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against synthetic phosphopeptide of Mapk14.
- Immunogen:
- Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding T180/Y182 of rat Mapk14.
- Host:
- Mouse
- Reactivity:
- Human, Mouse, Rat
- Specificity:
- This peptide sequence is highly conserved in the p38b,g, and d MAPKs, and is identical in human and mouse p38a.
- Form:
- Liquid
- Isotype:
- IgG1
- Storage Buffer:
- In PBS (50% glycerol, 1 mg/mL BSA, 0.05% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- ELISA (1:2000)
Immunocytochemistry (1:250)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine.
Raingeaud J, Gupta S, Rogers JS, Dickens M, Han J, Ulevitch RJ, Davis RJ.J Biol Chem. 1995 Mar 31;270(13):7420-6.
- 2.
- Interleukin-1 activates a novel protein kinase cascade that results in the phosphorylation of Hsp27.
Freshney NW, Rawlinson L, Guesdon F, Jones E, Cowley S, Hsuan J, Saklatvala J.Cell. 1994 Sep 23;78(6):1039-49.
- 3.
- A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins.
Rouse J, Cohen P, Trigon S, Morange M, Alonso-Llamazares A, Zamanillo D, Hunt T, Nebreda AR.Cell. 1994 Sep 23;78(6):1027-37.
- Entrez GeneID:
- 81649
- Gene Name:
- Mapk14
- Gene Alias:
- CSBP,CSPB1,Csbp1,Csbp2,Exip,Hog,MGC105413,Mxi2,Prkm14,Prkm15,RK,Sapk2A,p38,p38Hog,p38alpha
- Gene Description:
- mitogen activated protein kinase 14
- Gene Ontology:
- Hyperlink
- Other Designations:
- Csaids binding protein,MAP kinase 2,MAP kinase Mxi2,MAX-interacting protein 2,cytokine suppressive anti-inflammatory drug binding protein,cytokine-supressive anti-inflammatory drug binding protein,mitogen-activated protein kinase 14,p38 MAP kinase,p38 mit
- Interactome