KL polyclonal antibody
产品名称: KL polyclonal antibody
英文名称: KL polyclonal antibody
产品编号: PAB15643
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised aganist synthetic peptide of KL.
- Immunogen:
- A synthetic peptide corresponding to amino acids at internal region of human KL.
- Sequence:
- NQSQVNHTILQYYRC
- Host:
- Goat
- Theoretical MW (kDa):
- 116
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Insulin stimulates the cleavage and release of the extracellular domain of Klotho by ADAM10 and ADAM17.
Chen CD, Podvin S, Gillespie E, Leeman SE, Abraham CR.Proc Natl Acad Sci U S A. 2007 Dec 11;104(50):19796-801. Epub 2007 Dec 3.
- Application Image
- ELISA
- Entrez GeneID:
- 9365
- Protein Accession#:
- NP_004786.2
- Gene Name:
- KL
- Gene Alias:
- -
- Gene Description:
- klotho
- Omim ID:
- 604824
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a type-I membrane protein that is related to beta-glucosidases. Reduced production of this protein has been observed in patients with chronic renal failure (CRF), and this may be one of the factors underlying the degenerative processes (e.g., arteriosclerosis, osteoporosis, and skin atrophy) seen in CRF. Also, mutations within this protein have been associated with ageing and bone loss. [provided by RefSeq
- Other Designations:
- OTTHUMP00000018796
- Related Disease
- Acute Disease
- Aging, Premature
- Alzheimer disease
- Anemia, Sickle Cell
- Anemia, sickle cell
- Angina Pectoris, Variant
- Atherosclerosis
- Atherosclerosis
- Brain Ischemia
- Breast Neoplasms
- Calcinosis
- Cardiomyopathies
- Cardiovascular Diseases
- Carotid Artery Diseases
- Cerebrovascular Accident
- Chromosome Disorders
- Cognition
- Connective Tissue Diseases
- Coronary Artery Disease